
At Total Skin, we are always looking for therapies that support our patients not just aesthetically, but at a foundational, cellular level. One of the most exciting regenerative wellness options available today is NAD+ peptide therapy.
If you’re feeling fatigued, foggy, inflamed, hormonally depleted, or simply not like yourself, NAD+ may be the missing piece for you.
Let’s break down what it is, who it’s for, and why it’s becoming one of the most requested bio-optimization therapies.
What is NAD+?
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in every cell of your body. It plays a critical role in:
- Cellular energy production (ATP)
- DNA repair
- Mitochondrial function
- Brain health
- Hormone regulation
- Metabolic efficiency
- Healthy aging processes
As we age, NAD+ levels naturally decline, starting as early as our 30s. Stress, poor sleep, alcohol use, chronic inflammation, and metabolic dysfunction accelerate this decline.
NAD+ peptide therapy helps restore those levels to support optimal function from the inside out.
Benefits of NAD+ Peptide Therapy
Increased Energy
Supports mitochondrial function and ATP production ( your cells’ energy currency).
Improved Cognitive Function
May enhance focus, memory, mental clarity, and reduce brain fog.
Reduced Inflammation
Supports cellular repair and may help regulate inflammatory pathways.
Enhanced Muscle Recovery
Popular among active individuals and those healing from stress or training fatigue.
Better Sleep Regulation
Improved cellular function often translates into improved sleep cycles.
Metabolic Support
Can complement weight management programs by improving metabolic efficiency.
Healthy Aging
Supports sirtuin activation — proteins associated with longevity and cellular repair.
Who Is NAD+ Therapy For?
NAD+ therapy may be appropriate for individuals who:
- Feel chronically fatigued
- Experience brain fog
- Are under high stress
- Are starting BHRT or optimizing hormones
- Are in perimenopause or menopause
- Are focused on longevity and preventative wellness
- Have metabolic concerns
- Want enhanced recovery from workouts
- Desire to improve mental performance
Ideal Demographic
- While adults of various ages can benefit, it is most utilized by:
- Men and women 30–65+
- High-performing professionals
- Busy parents
- Active individuals
- Patients undergoing hormone optimization
- Individuals invested in preventative and regenerative medicine
At Total Skin, many of our middle-class to luxury wellness-focused clients appreciate therapies that improve how they feel, not just how they look, and NAD+ aligns beautifully with that philosophy.
Dosing & Administration
NAD+ peptide therapy can be administered in several ways:
Subcutaneous Injections, Oral and by IV infusion.
Combination Protocols
Often paired with:
- BPC-157
- Glutathione
- MIC injections
- Vitamin D optimization
- Hormone replacement therapy
Dosing is individualized after a comprehensive consult. We never take a one-size-fits-all approach.
Possible Side Effects
NAD+ is generally well tolerated, but potential side effects may include:
- Mild nausea (more common with IV)
- Headache
- Flushing
- Injection site irritation
- Fatigue during initial dosing (as the body adjusts)
Side effects are typically mild and temporary. Proper dosing and administration technique significantly reduce risk.
Who Should Avoid NAD+ Therapy?
NAD+ may not be appropriate for:
- Pregnant or breastfeeding individuals
- Those with certain active cancers (consult required)
- Individuals with severe uncontrolled medical conditions
- Anyone without proper medical screening
- A thorough medical history and provider consultation are required prior to starting therapy.
Why Choose Total Skin?
At Total Skin, we believe true aesthetic wellness begins at the cellular level. When your energy is optimized, your skin glows differently. Your hormones balance more effectively. Your treatment outcomes perform better.
We combine: Medical oversight, personalized dosing, functional wellness principles, ongoing monitoring, and a supportive, luxury experience. It’s not just about anti-aging treatment is about optimization, because we believe that normal is not always optimal!!
Is NAD+ Right for You?
If you are feeling: Tired but wired, foggy but functional stressed but pushing through or simply wanting to age proactively NAD+ peptide therapy may be a powerful addition to your wellness plan.
Schedule a consultation at Total Skin to determine if NAD+ is appropriate for your individual goals.
Because feeling vibrant is the foundation of looking radiant!!

